Dr. Anderson is a founding member of the Duquesne University Center for Pharmaceutical Technology (DCPT). His current focus is on building and leading a research group to explore new and existing analytical technologies and demonstrate their relevance to process analytical technology (PAT) applications. In addition to exploring PAT tools, his group uses these tools to enhance the understanding of the chemistry and physics of pharmaceutical technology. He has spent seven years working for the three different incarnations of the pharmaceutical company that became known as Aventis Pharmaceuticals. While there, he led the team that developed, validated, and implemented Aventis’ first PAT based methods. He served on the executive committee of the NIR Validation Working Group (NIRVWoG) that authored the revisions to USP, and currently serves on the ASTM E55 committee as a member at large on the board of directors.
Igne Benoit, Hanzhou Feng, James K. Drennen, III, Carl A. Anderson “Investigation of the Sensitivity of Transmission Raman Spectroscopy for Polymorphs Detection in Pharmaceutical Tablets” Applied spectroscopy – submitted
Igne Benoit, Arai Hiroaki, Drennen James K, Anderson Carl A “Effect of Sampling Frequency for Real-Time Tablet Coating Monitoring” Applied Spectroscopy (2016), 70(9), 1476-88
Yi Li, Benoit Igne, James K. Drennen, III, Carl A. Anderson “Method Development and Validation for Pharmaceutical Tablets Analysis Using Transmission Raman Spectroscopy” Int J Pharm. 2016, 498(1-2), 318-325
Igne Benoit, Sameer Talwar, Hanzhou Feng, James K. Drennen, III, Carl A. Anderson “Near- Infrared Spatially Resolved Spectroscopy for Tablet Quality Determination” Journal of Pharmaceutical Sciences. 2015, 104(12), 4074-4081
Wataru Momose, Jeffrey M. Katz, James K. Drennen III, Carl A. Anderson “Development of an NIR Method for Blend Analysis Using Small Quantities of Materials.” J Pharm Innov. (2015) 10, 36-46
Igne, Benoit; Drennen, James K., III; Anderson, Carl A. “Improving near-infrared prediction model robustness with support vector machine regression: a pharmaceutical tablet assay example” Applied Spectroscopy (2014), 68(12), 1348-1356.
Igne B, de Juan A, Jaumot J, Lallemand J, Preys S, Drennen JK, Anderson CA. “Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy” Int J Pharm. 2014 Oct 1;473(1-2):219-31.
Igne, Benoit; Hossain, Md. Nayeem; Drennen, James K., III; Anderson, Carl A. “Robustness considerations and effects of moisture variations on near infrared method performance for solid dosage form assay” Journal of Near Infrared Spectroscopy (2014), 22(3), 179-188
Igne, Benoit; Juan, Anna de; Jaumot, Joaquim; Lallemand, Jordane; Preys, Sebastien; Drennen, James K.; Anderson, Carl A. “Modeling strategies for pharmaceutical blend monitoring and end- point determination by near- infrared spectroscopy” Journal of Pharmaceutical sciences, 2014, 473 (1-2), 219-231
Jaumot, J.; Igne, B.; Anderson, C. A.; Drennen, J. K.; de Juan, A. “Blending process modeling and control by multivariate curve resolution” Talanta, 2013, 117, 492-504
Igne B, Shi Z, Drennen JK 3rd, Anderson CA. “Effects and detection of raw material variability on the performance of near-infrared calibration models for pharmaceutical products.” J Pharm Sci. 2014 Feb;103(2):545-56
Igne B., Talwar S., Drennen J.K. III, Anderson, C.A.; Online Monitoring of Pharmaceutical Materials Using Multiple NIR Sensors—Part II: Blend End-point Determination. Journal of Pharmaceutical Innovation, 2013, 8(1) 45-55
Bondi, R.W.; Igne, B.; Drennen, J.K.; Anderson, C.A.; Effect of Experimental Design on the Prediction Performance of Calibration Models Based on Near-Infrared Spectroscopy for Pharmaceutical Applications. Applied Spectroscopy, 2012, 66 (12), 1442-1453
Book Chapter: C. A. Anderson, E. W. Ciurczak, and J. K. Drennen, “Pharmaceutical Applications of Near-Infrared Spectroscopy” in D. A. Burns, E. W. Ciurczak, Handbook of Near-Infrared Analysis, 3rd Edition (Practical Spectroscopy), CRC Press 2007 ISBN: 978-0849373930